Publications

MP Kolevar, A Koshar, J Hirsch, RH Choe‡, J Wu, MS Rocca, S McLoughlin‡, A Veneble-Croft‡, JP Fisher, and JD Packer*. Development of a Patient Specific Cartilage Graft Using Magnetic Resonance Imaging and 3D Printing. Journal of ISAKOS. In Press. DOI

SM Kronstadt, DB Patel, LJ Born, D Levy, M Lerman‡, B Mahadik‡, S McLoughlin‡, A Fasuyi, L Fowlkes, LH Van Heyningen, A Aranda, SN Abadchi, KH Chang, ATW Hsu, S Bengali, JW Harmon, JP Fisher, SM Jay*. Mesenchymal Stem Cell Culture within Perfusion Bioreactors Incorporating 3D‐Printed Scaffolds Enables Improved Extracellular Vesicle Yield with Preserved Bioactivity. Advanced Healthcare Materials. 2300584 (2023). (DOI)

 ER Komosa, WH Lin, B Mahadik‡, M Bazzi, D Townsend, JP Fisher, BM Ogle*. A Novel Perfusion Bioreactor Promotes the Expansion of Pluripotent Stem Cells in a 3D-Bioprinted Tissue Chamber. Biofabrication. In Press. (DOI)

 F Fahma, A Firmanda, J Cabral, D Pletzer, JP Fisher, B Mahadik‡, IW Arnata, D Sartika, and A Wulandari*. Three-Dimensional Printed Cellulose for Wound Dressing Applications. 3D Printing and Additive Manufacturing. 10: 1015-1035 (2023). (DOI)

RH Choe‡, BC Kuzemchak‡, GJ Kotsanos‡, E Mirdamadi‡, M Sherry‡, E Devoy, T Lowe, JD Packer, and JP Fisher*. Designing Biomimetic 3D-Printed Osteochondral Scaffolds for Enhanced Physiological Load-Bearing Capacity. Tissue Engineering Part A. In Press. (DOI)

ST McLoughlin, AR McKenna, and JP Fisher.* Fabrication Strategies for Engineered Thin Membranous Tissues. ACS Applied Bio Materials. In Press. (DOI)

BC Kuzemchak, RH Choe, M Sherry, E Porter, and JP Fisher.* 3D Printable Phantom for Mimicking Electrical Properties of Dermal Tissue. Journal of Biomedical Materials Research, Part A. In Press. (DOI)

ST McLoughlin, AR McKenna, and JP Fisher.* 4D Bioprinting via Molecular Network Contraction for Membranous Tissue Fabrication. Advanced Healthcare Materials. (DOI)

C Johnson, H Aranda-Espinoza, JP Fisher.* A Case for Material Stiffness as a Design Parameter in Encapsulated Islet Transplantation. Tissue Engineering Part B, Reviews. In Press. (DOI)

C Johnson, D Fischer, I Smith, H Aranda-Espinoza, JP Fisher.* Hyperglycemic Conditions Enhance the Mechanosensitivity of Proinflammatory RAW264.7 Macrophages. Tissue Engineering Part A. In Press. (DOI)

K Fogg, NH Tseng, SR Peyton, P Holeman, S McLoughlin, JP Fisher, A Sutton, A Shikanov, JS Gnecco, KM Knight, EM Slaby, JD Weaver, NN Hashemi, Y Zhang, MD House, BJ Vogt, BA Aguado, JBradford, JL Robinson, PK Thomas, AG Lau, and ML Oyen*. Roadmap on Biomaterials for Women’s Health. Journal of Physics: Materials. 6: 012501 (2023). (DOI)

Born, L. J., McLoughlin, S. T., Dutta, D., Mahadik, B., Jia, X., Fisher, J. P., & Jay, S. M. (2022). Sustained released of bioactive mesenchymal stromal cell-derived extracellular vesicles from 3D-printed gelatin methacrylate hydrogels. Journal of biomedical materials research. Part A, 110(6), 1190–1198. DOI: 10.1002/jbm.a.37362

Sarti, M., Parlani, M., Diaz-Gomez, L., Mikos, A. G., Cerveri, P., Casarin, S., & Dondossola, E. (2022). Deep Learning for Automated Analysis of Cellular and Extracellular Components of the Foreign Body Response in Multiphoton Microscopy Images. Frontiers in bioengineering and biotechnology, 9, 797555. DOI: 10.3389/fbioe.2021.797555

Hogan, K. J., Smoak, M. M., Koons, G. L., Perez, M. R., Bedell, M. L., Jiang, E. Y., Young, S., & Mikos, A. G. (2022). Bioinspired electrospun decellularized extracellular matrix scaffolds promote muscle regeneration in a rat skeletal muscle defect model. Journal of biomedical materials research. Part A, 110(5), 1090–1100. DOI: 10.1002/jbm.a.37355

B Mahadik, S McLoughlin, R Margolis, A Melchiorri, SJ Lee, J Yoo, A Atala, AG Mikos, and JP Fisher*. An Open-Source Bioink Database for Microextrusion 3D Printing. Biofabrication. 15: 015008 (2022). (DOI)

CH Stuelten, N Melis, B Subramanian, Y Tang, M Kimicata, JP Fisher, R Weigert, and YE Zhang*. Smurf2 Negatively Regulates Wound Healing Through TGF-Beta/Smad3 Signaling. The American Journal of Pathology. 192: 1699-1711 (2022)(PudMed)

Z Li, Z Lin, S Liu, H Yagi, X Zhang, L Yocum, M Romero-Lopez, C Rhee, MJ Makarcyzk, EN Li,
MR Fritch, Q Gao, KB Goh, B O’Donnell, T Hao, PG Alexander, B Mahadik, JP Fisher, SB Goodman, BA Bunnell, RS Tuan, H Lin*. Human Mesenchymal Stem Cell-Derived Miniature Joint System for Disease Modeling and Drug Testing. Advanced Science. 9: 105909 (2022). (DOI)

JY Choi, SF Yee, T Tchangalova, G Yang, and JP Fisher*. Recent Advances in Senotherapeutics Delivery. Tissue Engineering Part B Reviews. 28: 1223-1234 (2022). (DOI)

B Jiang, W Ou, JG Shamul, H Chen, S Van Belleghem, S Stewart, Z Liu, JP Fisher, and X He*. Rock Inhibitor May Compromise Human Induced Pluripotent Stem Cells for Cardiac Differentiation in 3D. Bioactive Materials. 9: 508-522 (2022). (PubMed)

R Choe, E Devoy, E Jabari, JD Packer, and JP Fisher*. Biomechanical Aspects of Osteochondral Regeneration: Implications and Strategies for 3D Bioprinting. Tissue Engineering Part B Reviews. (2022). (PubMed)

JR Yu, P Varreya, BJ Liang, HC Huang, and JP Fisher*. Liposomal SDF-1 Alpha Delivery in Nanocomposite Hydrogels Promotes Macrophage Phenotype Changes and Skin Tissue Regeneration. ACS Biomaterials Science & Engineering. In Press. (PubMed)

A Firmanda K Syamsu, Y W Sari, J Cabral, D Pletzer, B Mahadik, JP Fisher, and F Fahma*. 3D Printed Cellulose Based Product Applications. Materials Chemistry Frontiers (2022). (DOI)

R Choe, E Devoy, B Kuzemchak, M Sherry, E Jabari, JD Packer, and JP Fisher*. Computational Investigation of Interface Printing Patterns Within 3D Printed Multilayered Scaffolds for Osteochondral Tissue Engineering. Biofabrication (2022). (PubMed)

B Jiang, A White, W Ou, S Van Belleghem, S Stewart, J Shamul, JP Fisher, and X He. Noncovalent Reversible Binding-Enabled Facile Fabrication of Leak-Free PDMS Microfluidic Devices for Convenient Cell Loading and Retrieval. Bioactive Materials (2022). (PubMed)

Yang G, Mahadik B, Choi JY, Yu JR, Mollot T, Jiang B, He X, and Fisher JP. Fabrication of centimeter-sized 3D constructs with patterned endothelial cells through assembly of cell-laden microbeads as a potential bone graft. Acta Biomaterialia 121 (2021) 204–213. PMID: 33271356. PMCID: PMC785573. DOI: 10.1016/j.actbio.2020.11.040 

Gete YG, Koblan LW, Mao X, Trappio M, Mahadik B, Fisher JP, Liu DR, Cao K. Mechanisms of angiogenic incompetence in Hutchinson-Gilford progeria via downregulation of endothelial NOS. Aging Cell. 2021 Jun 4;e13388. PMID: 34086398. DOI: 10.1111/acel.13388

Visscher DO, Lee H, van Zukjlen PPM, Helder MN, Atala A, Yoo JJ, Lee SJ. Development and characterization of a tissue-specific, extracellular matrix bioink for elastic cartilage bioprinting. Acta Biomater, 2021;121:193-203. PMID: 33227486 PMCID: PMC7855948 

Kim SH, Kwon JS, Cho JG, Park KG, Lim TH, Kim MS, Choi HS, Park CH, Lee SJ. Non-invasive in vivo monitoring of transplanted stem cells in 3D-bioprinted constructs using near-infrared fluorescent imaging. Bioeng Transl Med, 2021;e10216. PMID: 34027098. PMCID: PMC8126817. DOI: 10.1002/btm2.10216

Lee H, Kim WJ, Lee JU, Yoo JJ, Atala A, Kim GH, Lee SJ. Self-aligned myofibers in 3D bioprinted extracellular matrix-based construct accelerate skeletal muscle function restoration. Appl Phys Rev, 2021; 8:021405. PMID: 34084255 PMCID: PMC8117312. DOI: 10.1063/5.0039639

Huh JT, Moon Y-W, Park J, Atala A, Yoo JJ, Lee SJ. Optimization of photoinitiator and UV absorber for digital light processing bioprinting. Biofabrication, 2021;13(3):034103. PMID: 33930877 

Kim YS, Mikos AG. Emerging Strategies in Reprogramming and Enhancing the Fate of Mesenchymal Stem Cells for Bone and Cartilage Tissue Engineering. Journal of Controlled Release, 330:565-574, 2021 Feb. PMID: 33388339, DOI: 10.1016/j.jconrel.2020.12.055

Guo JL, Diaz-Gomez L, Xie VY, Bittner SM, Jiang EY, Wang B, and Mikos AG. Three-Dimensional Printing of Click Functionalized, Peptide Patterned Scaffolds for Osteochondral Tissue Engineering. Bioprinting, 22, e00136 (9pp) (2021). DOI: 10.1016/j.bprint.2021.e00136

Peper S, Vo T, Ahuja N, Awad K, Mikos AG, and Varanasi V. Bioprinted Nanocomposite Hydrogels: A Proposed Approach to Functional Restoration of Skeletal Muscle and Vascular Tissue Following Volumetric Muscle Loss. Curr. Opin. Pharmacol., 58, 35-43 (2021). DOI: 10.1016/j.coph.2021.03.005

Smoak MM, Hogan KJ, Grande-Allen KJ, and Mikos AG. Bioinspired Electrospun dECM Scaffolds Guide Cell Growth and Control the Formation of Myotubes, Science Adv., 7, eabg4123 (12pp) (2021). DOI: 10.1126/sciadv.abg4123

Diba M, Koons GL, Bedell ML, and Mikos AG. 3D Printed Colloidal Biomaterials Based on Photo-Reactive Gelatin Nanoparticles. Biomaterials, 274, 120871 (16pp) (2021). DOI: 10.1016/j.biomaterials.2021.120871

Bittner SM, Pearce HA, Hogan KJ, Smoak MM,  Guo JL, Melchiorri AJ, Scott DW, and Mikos AG. Swelling Behaviors of 3D Printed Hydrogel and Hydrogel-Microcarrier Composite Scaffolds. Tissue Eng. Part A, 27, 665-678 (2021). DOI: 10.1089/ten.TEA.2020.0377

Pearce HA,  Kim YS, Watson E, Bahrami K, Smoak MM, Jiang EY, Elder M, Shannon T, and Mikos AG. Development of a Modular, Biocompatible Thiolated Gelatin Microparticle Platform for Drug Delivery and Tissue Engineering Applications. Regener. Biomater., 8, rbab012 (12pp) (2021). DOI: 10.1093/rb/rbab012

Kimicata, M., Mahadik, B., & Fisher, J. P. (2021). Long-Term Sustained Drug Delivery via 3D Printed Masks for the Development of a Heparin-Loaded Interlayer in Vascular Tissue Engineering Applications. ACS applied materials & interfaces, 13(43), 50812–50822. DOI: 10.1021/acsami.1c16938 

Choi, J. Y., Mahadik, B., & Fisher, J. P. (2021). 3D printing technologies for in vitro vaccine testing platforms and vaccine delivery systems against infectious diseases. Essays in biochemistry, 65(3), 519–531. DOI: 10.1042/EBC20200105

Yang, G., Mahadik, B., Choi, J. Y., Yu, J. R., Mollot, T., Jiang, B., He, X., & Fisher, J. P. (2021). Fabrication of centimeter-sized 3D constructs with patterned endothelial cells through assembly of cell-laden microbeads as a potential bone graft. Acta biomaterialia, 121, 204–213. DOI: 10.1016/j.actbio.2020.11.040

Choe, R., Devoy, E., Jabari, E., Packer, J. D., & Fisher, J. P. (2021). Biomechanical Aspects of Osteochondral Regeneration: Implications and Strategies for Three-Dimensional Bioprinting. Tissue engineering. Part B, Reviews, DOI: 10.1089/ten.TEB.2021.0101.

Gete, Y. G., Koblan, L. W., Mao, X., Trappio, M., Mahadik, B., Fisher, J. P., Liu, D. R., & Cao, K. (2021). Mechanisms of angiogenic incompetence in Hutchinson-Gilford progeria via downregulation of endothelial NOS. Aging cell, 20(7), e13388. DOI: 10.1111/acel.13388

Yu, J. R., Varrey, P., Liang, B. J., Huang, H. C., & Fisher, J. P. (2021). Liposomal SDF-1 Alpha Delivery in Nanocomposite Hydrogels Promotes Macrophage Phenotype Changes and Skin Tissue Regeneration. ACS biomaterials science & engineering, 7(11), 5230–5241. DOI: 10.1021/acsbiomaterials.1c01140

Allbritton-King, J. D., Kimicata, M., & Fisher, J. P. (2021). Incorporating a structural extracellular matrix gradient into a porcine urinary bladder matrix-based hydrogel dermal scaffold. Journal of biomedical materials research. Part A, 109(10), 1893–1904. DOI: 10.1002/jbm.a.37181

Visscher, D. O., Lee, H., van Zuijlen, P., Helder, M. N., Atala, A., Yoo, J. J., & Lee, S. J. (2021). A photo-crosslinkable cartilage-derived extracellular matrix bioink for auricular cartilage tissue engineering. Acta biomaterialia, 121, 193–203. PMCID: PMC7855948. DOI: 10.1016/j.actbio.2020.11.029

Huh, J., Moon, Y. W., Park, J., Atala, A., Yoo, J. J., & Lee, S. J. (2021). Combinations of photoinitiator and UV absorber for cell-based digital light processing (DLP) bioprinting. Biofabrication, 13(3), DOI: 10.1088/1758-5090/abfd7a

Y.S. Kim, S.M. Mehta, J.L. Guo, H.A. Pearce, B.T. Smith, E. Watson, G.L. Koons, A.M. Navara, J. Lam, K.J. Grande-Allen, and A.G. Mikos, “Evaluation of Tissue Integration of Injectable, Cell-Laden Hydrogels of Cocultures of Mesenchymal Stem Cells and Articular Chondrocytes with an Ex Vivo Cartilage Explant Model,” Biotechnol. Bioeng., 118, 2958-2966 (2021).

Koons, G. L., Kontoyiannis, P. D., Diba, M., Chim, L. K., Scott, D. W., & Mikos, A. G. (2021). Effect of 3D Printing Temperature on Bioactivity of Bone Morphogenetic Protein-2 Released from Polymeric Constructs. Annals of biomedical engineering, 49(9), 2114–2125. DOI: 10.1007/s10439-021-02736-9

Bello, T., Paindelli, C., Diaz-Gomez, L. A., Melchiorri, A., Mikos, A. G., Nelson, P. S., Dondossola, E., & Gujral, T. S. (2021). Computational modeling identifies multitargeted kinase inhibitors as effective therapies for metastatic, castration-resistant prostate cancer. Proceedings of the National Academy of Sciences of the United States of America, 118(40), e2103623118. DOI: 10.1073/pnas.2103623118

Melendez, B., Shah, S., Jiang, Y., Dottino, J., Watson, E., Pearce, H., Borthwick, M., Schmandt, R. E., Zhang, Q., Cumpian, K., Celestino, J., Fellman, B., Yuan, Y., Lu, K. H., Mikos, A. G., & Yates, M. S. (2021). Novel polymer-based system for intrauterine delivery of everolimus for anti-cancer applications. Journal of controlled release : official journal of the Controlled Release Society, 339, 521–530. DOI: 10.1016/j.jconrel.2021.10.008 

Paindelli C, Casarin S, Wang F, Diaz-Gomez L, Zhang J, Mikos AG, Logothetis CJ, Friedl P, Dondossola E. Enhancing Radium 223 treatment efficacy by anti-beta 1 integrin targeting. J Nucl Med. 2021 Oct 28:jnumed.121.262743. Epub ahead of print. PMID: 34711616. PMID: 34711616. DOI: 10.2967/jnumed.121.262743

Pearce HA, Jiang EY, Swain JWR, Navara AM, Guo JL, Kim YS, Woehr A, Hartgerink JD, Mikos AG. Evaluating the physicochemical effects of conjugating peptides into thermogelling hydrogels for regenerative biomaterials applications. Regen Biomater. 2021 Dec 13;8(6):rbab073. PMID: 34934509; PMCID: PMC8684499. DOI: 10.1093/rb/rbab073

Navara AM, Kim YS, Xu Y, Crafton CL, Diba M, Guo JL, Mikos AG. A dual-gelling poly(N-isopropylacrylamide)-based ink and thermoreversible poloxamer support bath for high-resolution bioprinting. Bioact Mater. 2021 Nov 19;14:302-312. PMID: 35310364; PMCID: PMC8897628. DOI: 10.1016/j.bioactmat.2021.11.016

Guo JL, Kim YS, Orchard E, van der Beucken J, Jansen JA, Wong MEK, Mikos AG. A Rabbit Femoral Condyle Defect Model for Assessment of Osteochondral Tissue Regeneration. Tissue Engineering Part C Methods, 2020 Nov. PMID: 33050806, DOI: 10.1089/ten.TEC.2020.0261

Conev A, Litsa EE, Perez MR, Diba M, Mikos AG, Kavraki LE. Machine Learning-Guided Three-Dimensional Printing of Tissue Engineering Scaffolds. Tissue Engineering Part A, 2020 Oct. PMID: 32940144, DOI: 10.1089/ten.TEA.2020.0191

Gillispie GJ, Han A, Uzun-Per M, Fisher JP, Mikos AG, Niazi MKK, Yoo JJ, Lee SJ, Atala A. The Influence of Printing Parameters and Cell Density on Bioink Printing Outcomes. Tissue Engineering Part A, 2020 Oct. PMID: 32928068, NIHMSID: 1633376, DOI: 10.1089/ten.tea.2020.0210

Watson E, Smith BT, Smoak MM, Tatara AM, Shah SR, Pearce HA, Hogan KJ, Shum J, Melville JC, Hanna IA, Demian N, Wenke JC, Bennett GN, van den Beucken JJJP, Jansen JA, Wong ME, Mikos AG. Localized Mandibular Infection Affects Remote In Vivo Bioreactor Bone Generation. Biomaterials, 256: 120185, 2020 Oct. PMID: 32599360, PMCID: PMC7423761, DOI: 10.1016/j.biomaterials.2020.120185

Yang G, Mahadik B, Mollot T, Pinsky J, Jones A, Robinson A, Najafali D, Rivkin D, Katsnelson J, Piard C, Fisher JP. Engineered Liver Tissue Culture in an in-vitro Tubular Perfusion System. Tissue Engineering Part A. 2020 Oct. PMID: 33054685, DOI: 10.1089/ten.TEA.2020.0213

Costa JB, Park J, Silva-Correia J, Reis RL, Oliverira JM, Atala A, Yoo JJ, Lee SJ. 3D Bioprinted Highly Elastic Hybrid Constructs for Advanced Fibrocartilaginous Tissue Regeneration. Chemistry of Materials, 32(19):8733-8746, 2020 Sept. DOI: 10.1021/acs.chemmater.0c03556

Kim YS, Chien AJ, Guo JL, Smith BT, Watson E, Pearce HA, Koons GL, Navara AM, Lam J, Scott DW, Grande-Allen KJ, Mikos AG. Chondrogenesis of Cocultures of Mesenchymal Stem Cells and Articular Chondrocytes in Poly(l-lysine)-loaded Hydrogels. Journal of Controlled Release, 328: 710-721, 2020 Sep. PMID: 33010336, DOI: 10.1016/j.jconrel.2020.09.048

Piard C, Luthcke R, Kamalitdinov T, Fisher JP. Sustained Delivery of Vascular Endothelial Growth Factor from Mesoporous Calcium‐deficient Hydroxyapatite Microparticles Promotes in vitro Angiogenesis and Osteogenesis. Journal of Biomedical Materials Research A, 2020 Sep. PMID: 32918524, NIHMSID: NIHMS1643010, DOI: 10.1002/jbm.a.37100

Kim SH, Park JH, Kwon JS, Cho JG, Park KG, Park CH, Yoo JJ, Atala A, Choi HS, Kim MS, Lee SJ. NIR Fluorescence for Monitoring in vivo Scaffold Degradation Along With Stem Cell Tracking in Bone Tissue Engineering. Biomaterials, 258:120267, 2020 Aug. PMID: 32781325, PMCID: PMC7484145, DOI: 10.1016/j.biomaterials.2020.120267

Hurley-Novatny A, Arumugasaamy N, Kimicata M, Baker H, Mikos AG, Fisher JP. Concurrent Multi-lineage Differentiation of Mesenchymal Stem Cells Through Spatial Presentation of Growth Factors. Biomedical Materials, 15(5): 055035, 2020 Aug. PMID: 32526725, PMCID: PMC7648258, DOI: 10.1088/1748-605X/ab9bb0

Lee SC, Gillispie G, Prim P, Lee SJ. Physical and Chemical Factors Influencing the Printability of Hydrogel-based Extrusion Bioinks. Chemical Reviews, 120:10834-10886, 2020 Aug. PMID: 32815369, NIHMSID: 1640931, DOI: 10.1021/acs.chemrev.0c00015

Farr AC, Hogan KJ, Mikos AG. Nanomaterial Additives for Fabrication of Stimuli-Responsive Skeletal Muscle Tissue Engineering Constructs. Advanced Healthcare Materials, e2000730, 2020 Jul. PMID: 32691983, DOI: 10.1002/adhm.202000730

Spiliopoulos M, Kuo C, Eranki A, Jacobs M, Rossi C, Iqbal S, Fisher JP, Fries M, Kim PCW. Characterizing Placental Stiffness Using Ultrasound Shear-wave Elastography in Healthy and Preeclamptic Pregnancies. Archives of Gynecology and Obstetrics, 302(5): 1103-1112, 2020 Jul. PMID: 32676857, PMCID: PMC7646518, DOI: 10.1007/s00404-020-05697-x

Kimicata M, Allbritton-King J, Navarro J, Santoro M, Inoue T, Hibino N, Fisher JP. Assessment of Decellularized Pericardial Extracellular Matrix and Poly(propylene fumarate) Biohybrid for Small-Diameter Vascular Graft Applications. Acta Biomaterialia, 110: 68-81, 2020 Jul. PMID: 32305447 PMCID: PMC7294167, DOI: 10.1016/j.actbio.2020.04.013

Smoak MM, Mikos AG. Advances in Biomaterials for Skeletal Muscle Engineering and Obstacles Still to Overcome. Materials Today Bio, 7:100069, 2020 Jul. PMID: 32695987, PMCID: PMC7363708, DOI: 10.1016/j.mtbio.2020.100069

Park JH, Gillispie GJ, Copus JS, Zhang W, Atala A, Yoo JJ, Yelick PC, Lee SJ. The Effect of BMP-Mimetic Peptide Tethering Bioinks on the Differentiation of Dental Pulp Stem Cells (DPSCs) in 3D Bioprinted Dental Constructs. Biofabrication, 12(3): 035029, 2020 Jul. PMID: 32428889, DOI: 10.1088/1758-5090/ab9492

Watson E, Tatara AM, van der Beucken JJJP, Jansen JA, Wong ME, Mikos AG. An Ovine Model of In Vivo Bioreactor-Based Bone Generation. Tissue Engineering Part C Methods, 26(7): 384-396, 2020 Jul. PMID: 32536266, PMCID: PMC7398437, DOI: 10.1089/ten.tec.2020.0125

West-Livingston LN, Park J, Lee SJ, Atala A, and Yoo JJ. The Role of the Microenvironment in Controlling the Fate of Bioprinted Stem Cells. Chemical Reviews, 2020 Jun. PMID: 32558555, DOI: 10.1021/acs.chemrev.0c00126

Diaz-Gomez L, Elizondo ME, Kontoyiannis PD, Koons GL, Dacunha-Marinho B, Zhang X, Ajayan P, Jansen JA, Melchiorri AJ, Mikos AG. Three-Dimensional Extrusion Printing of Porous Scaffolds Using Storable Ceramic Inks. Tissue Engineering Part C: Methods, 26(6): 292-305, 2020 Jun. PMID: 32326874, PMCID: PMC7310315, DOI: 10.1089/ten.TEC.2020.0050

Diaz-Gomez L, Elizondo ME, Koons GL, Diba M, Chim LK, Cosgriff-Hernandez E, Melchiorri AJ, Mikos AG. Fiber Engraving for Bioink Bioprinting within 3D Printed Tissue Engineering Scaffolds. Bioprinting, 18: e00076 (8pp), 2020 Jun. DOI: 10.1016/j.bprint.2020.e00076

Molina ER, Chim LK, Barrios S, Ludwig JA, Mikos AG. Modeling the Tumor Microenvironment and Pathogenic Signaling in Bone Sarcoma. Tissue Engineering Part B: Reviews, 26(3): 249-271, 2020 Jun. PMID: 32057288, PMCID: PMC7310212, DOI: 10.1089/ten.teb.2019.0302

Bedell ML, Navara AM, Du Y, Zhang S, Mikos AG. Polymeric Systems for Bioprinting. Chemical Reviews, 120(19):10744-10792, 2020 May. PMID: 32469510, DOI: 10.1021/acs.chemrev.9b00834

Yu JR, Janssen M, Liang BJ, Huang HC, Fisher JP. A Liposome/Gelatin Methacrylate Nanocomposite Hydrogel System for Delivery of Stromal Cell-Derived Factor-1α and Stimulation of Cell Migration. Acta Biomaterialia, 108: 67-76, 2020 May. PMID: 32194261, PMCID: PMC7198368, DOI: 10.1016/j.actbio.2020.03.015

Navarro J, Clohessy RM, Holder RC, Gabard AR, Herendeen GJ, Christy RJ, Burnett LR, Fisher JP. In Vivo Evaluation of Three-Dimensional Printed, Keratin-Based Hydrogels in a Porcine Thermal Burn Model. Tissue Engineering Part A, 26(5-6): 265-278, 2020 Mar. PMID: 31774034, DOI: 10.1089/ten.TEA.2019.0181

Placone JK, Mahadik B, Fisher JP. Addressing Present Pitfalls in 3D Printing for Tissue Engineering to Enhance Future Potential. APL Bioengineering, 4(1): 010901, 2020 Mar. PMID: 32072121, PMCID: PMC7010521, DOI: 10.1063/1.5127860

Smith BT, Bittner SM, Watson E, Smoak MM, Diaz-Gomez L, Molina ER, Kim YS, Hudgins CD, Melchiorri AJ, Scott DW, Grande-Allen KJ, Yoo JJ, Atala A, Fisher JP, Mikos AG. Multimaterial Dual Gradient Three-Dimensional Printing for Osteogenic Differentiation and Spatial Segregation. Tissue Engineering Part A, 26(5-6): 239-252, 2020 Mar. PMID: 31696784, PMCID: PMC7133451, DOI: 10.1089/ten.TEA.2019.0204

Gillispie G, Prim P, Copus J, Fisher J, Mikos AG, Yoo JJ, Atala A, Lee SJ. Assessment Methodologies for Extrusion-Based Bioink Printability. Biofabrication, 12(2): 022003, 2020 Feb. PMID: 31972558, PMCID: PMC7039534, DOI: 10.1088/1758-5090/ab6f0d

Kim WJ, Lee HJ, Lee JU, Atala A, Yoo JJ, Lee SJ, Kum GH. Efficient Myotube Formation in 3D Bioprinted Tissue Construct by Biochemical and Topographical Cues. Biomaterials, 230: 119632, 2020 Feb. PMID: 31761486, DOI: 10.1016/j.biomaterials.2019.119632

Lerman MJ, Smith BT, Gerald AG, Santoro M, Fookes JA, Mikos AG, Fisher JP. Aminated 3D Printed Polystyrene Maintains Stem Cell Proliferation and Osteogenic Differentiation. Tissue Engineering Part C: Methods, 26(2): 118-131, 2020 Feb. PMID: 31971874, PMCID: PMC7041340, DOI: 10.1089/ten.tec.2019.0217

Van Belleghem S, Torres L, Santoro M, Mahadik B, Wolfand A, Kofinas P, Fisher JP. Hybrid 3D Printing of Synthetic and Cell-Laden Bioinks for Shape Retaining Soft Tissue Grafts. Advanced Functional Materials, 30(3):1907145, 2020 Jan. PMID: 33041744, PMCID: PMC7546434, DOI: 10.1002/adfm.201907145

Molina ER, Chim LK, Salazar MC, Koons GL, Menegaz BA, Ruiz-Velasco A, Lamhamedi-Cherradi SE, Vetter AM, Satish T, Cuglievan B, Scott DW, Ludwig JA, Mikos AG. 3D Tissue-Engineered Tumor Model for Ewing’s Sarcoma That Incorporates Bone-Like ECM and Mineralization. ACS Biomaterials Science & Engineering, 6: 539-552, 2020 Jan. DOI: 10.1021/acsbiomaterials.9b01068

Yang G, Mahadik B, Choi JY, Fisher JP. Vascularization in Tissue Engineering: Fundamentals and State-of-Art. Progress in Biomedical Engineering, 2: 012002, 2020 Jan. DOI: 10.1088/2516-1091/ab5637

Molina ER, Chim LK, Salazar MC, Mehta SM, Menegaz BA, Lamhamedi-Cherradi SE, Satish T, Mohiuddin S, McCall D, Zaske AM, Lazar AJ, Scott DW, Grande-Allen JK, Ludwig JA, Mikos AG. Mechanically Tunable Coaxial Electrospun Models of YAP/TAZ Mechanoresponse and IGF-1R Activation in Osteosarcoma. Acta Biomaterialia, 100: 38-51, 2019 Dec. PMID: 31542501, PMCID: PMC7027943, DOI: 10.1016/j.actbio.2019.09.029

Navarro J, Swayambunathan J, Janes ME, Santoro M, Mikos AG, Fisher JP. Dual-Chambered Membrane Bioreactor for Coculture of Stratified Cell Populations. Biotechnology and Bioengineering, 116: 3253-3268, 2019 Dec. PMID: 31502660, PMCID: PMC6834877, DOI: 10.1002/bit.27164

Lerman MJ, Muramoto S, Arumugasaamy N, Van Order M, Lembong J, Gerald AG, Gillen G, Fisher JP. Development of Surface Functionalization Strategies for 3D-Printed Polystyrene Constructs. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 107(8): 2566-2578, 2019 Nov. PMID: 30821930, DOI: 10.1002/jbm.b.34347

Piard C, Jeyaram A, Liu Y, Caccamese J, Jay SM, Chen Y, Fisher JP. 3D Printed HUVECs/MSCs Cocultures Impact Cellular Interactions and Angiogenesis Depending on Cell-Cell Distance. Biomaterials, 222: 119423, 2019 Nov. PMID: 31442885, PMCID: PMC6745276, DOI: 10.1016/j.biomaterials.2019.119423

Arumugasaamy N, Hurley-Novatny A, Lembong J, Kim PCW, Fisher JP. Assessing SSRIs' Effects on Fetal Cardiomyocytes Utilizing Placenta-Fetus Model. Acta Biomaterialia, 99: 258-268, 2019 Nov. PMID: 31536839, PMCID: PMC6851498, DOI: 10.1016/j.actbio.2019.09.019

Van Belleghem S, Torres Jr L,  Santoro M, Mahadik B, Wolfand A, Kofinas P, Fisher JP. Hybrid 3D Printing of Synthetic and Cell‐Laden Bioinks for Shape Retaining Soft Tissue Grafts. Advanced Functional Material, 30: 1907145, 2019 Oct. DOI: 10.1002/adfm.201907145

Arumugasaamy N, Hurley-Novatny A, Lembong J, Kim PCW, Fisher JP. Model Placental Barrier Phenotypic Response to Fluoxetine and Sertraline: A Comparative Study. Advanced Healthcare Materials, 8(18): e1900476, 2019 Sep. PMID: 31407872 PMCID: PMC6752965, DOI: 10.1002/adhm.201900476

Patel DB, Luthers CR, Lerman MJ, Fisher JP, Jay SM. Enhanced Extracellular Vesicle Production and Ethanol-Mediated Vascularization Bioactivity via a 3D-Printed Scaffold-Perfusion Bioreactor System. Acta Biomaterialia, 95: 236-244, 2019 Sep. PMID: 30471476, PMCID: PMC6531369, DOI: 10.1016/j.actbio.2018.11.024

Guo JL, Kim YS, Mikos AG. Biomacromolecules for Tissue Engineering: Emerging Biomimetic Strategies. Biomacromolecules, 20(8): 2904-2912, 2019 Aug. PMID: 31282658, DOI: 10.1021/acs.biomac.9b00792

Diaz-Gomez L, Kontoyiannis PD, Melchiorri AJ, Mikos AG. Three-Dimensional Printing of Tissue Engineering Scaffolds with Horizontal Pore and Composition Gradients. Tissue Engineering Part C: Methods, 25(7): 411-420, 2019 Jul. PMID: 31169080, PMCID: PMC6657302, DOI: 10.1089/ten.TEC.2019.0112

Guo JL, Kim YS, Xie VY, Smith BT, Watson E, Lam J, Pearce HA, Engel PS, Mikos AG. Modular, Tissue-Specific, and Biodegradable Hydrogel Cross-Linkers for Tissue Engineering. Science Advances, 5: eaaw7396, 2019 Jun. PMID: 31183408, PMCID: PMC6551165, DOI: 10.1126/sciadv.aaw7396

Bittner SM, Smith BT, Diaz-Gomez L, Hudgins CD, Melchiorri AJ, Scott DW, Fisher JP, Mikos AG. Fabrication and Mechanical Characterization of 3D Printed Vertical Uniform and Gradient Scaffolds for Bone and Osteochondral Tissue Engineering. Acta Biomaterialia, 90: 37-48, 2019 May. PMID: 30905862, PMCID: PMC6744258, DOI: 10.1016/j.actbio.2019.03.041

Smoak MM, Han A, Watson E, Kishan A, Grande-Allen KJ, Cosgriff-Hernandez E, Mikos AG. Fabrication and Characterization of Electrospun Decellularized Muscle-Derived Scaffolds. Tissue Engineering Part C: Methods, 25(5): 276-287, 2019 May. PMID: 30909819, PMCID: PMC6535957, DOI: 10.1089/ten.tec.2018.0339

Smoak MM, Pearce HA, Mikos AG. Microfluidic Devices for Disease Modeling in Muscle Tissue. Biomaterials, 198: 250-258, 2019 Apr. PMID: 30193908, PMCID: PMC6395563, DOI: 10.1016/j.biomaterials.2018.08.059

Tatara AM, Koons GL, Watson E, Piepergerdes TC, Shah SR, Smith BT, Shum J, Melville JC, Hanna IA, Demian N, Ho T, Ratcliffe A, van den Beucken JJJP, Jansen JA, Wong ME, Mikos AG. Biomaterials-Aided Mandibular Reconstruction Using In Vivo Bioreactors. Proceedings of the National Academy of Sciences of the USA, 116(14): 6954-6963, 2019 Apr. PMID: 30886100, PMCID: PMC6452741, DOI: 10.1073/pnas.1819246116

Ali M, PR AK, Yoo JJ, Zahran F, Atala A, Lee SJ. A Photo-Crosslinkable Kidney ECM-Derived Bioink Accelerates Renal Tissue Formation. Advanced Healthcare Materials, 8(7): e1800992, 2019 Apr. PMID: 30725520, PMCID: PMC7039535, DOI: 10.1002/adhm.201800992

Piard C, Baker H, Kamalitdinov T, Fisher JP. Bioprinted Osteon-like Scaffolds Enhance in vivo Neovascularization. Biofabrication, 11(2): 025013, 2019 Mar. PMID: 30769337, PMCID: PMC7195919, DOI: 10.1088/1758-5090/ab078a

Yu JR, Navarro J, Coburn JC, Mahadik B, Molnar J, Holmes JH, Nam AJ, Fisher JP. Current and Future Perspectives on Skin Tissue Engineering: Key Features of Biomedical Research, Translational Assessment, and Clinical Application. Advanced Healthcare Materials, 8(5): e1801471, 2019 Mar. PMID: 30707508, DOI: 10.1002/adhm.201801471

Koons GL and Mikos AG. Progress in Three-Dimensional Printing with Growth Factors. Journal of Controlled Release, 295: 50-59, 2019 Feb. PMID: 30579982, PMCID: PMC6358495, DOI: 10.1016/j.jconrel.2018.12.035

Diaz-Gomez L, Smith BT, Kontoyiannis PD, Bittner SM, Melchiorri AJ, Mikos AG. Multimaterial Segmented Fiber Printing for Gradient Tissue Engineering. Tissue Engineering Part C: Methods, 25(1): 12-24, 2019 Jan. PMID: 30421648, PMCID: PMC6352516, DOI: 10.1089/ten.tec.2018.0307

Kim YS, Smoak MM, Melchiorri AJ, Mikos AG. An Overview of the Tissue Engineering Market in the United States from 2011 to 2018. Tissue Engineering Part A, 25: 1-8, 2019 Jan. PMID: 30027831, PMCID: PMC6352506, DOI: 10.1089/ten.tea.2018.0138

Kuo CY, Shevchuk M, Opfermann J, Guo T, Santoro M, Fisher JP, Kim PC. Trophoblast-Endothelium Signaling Involves Angiogenesis and Apoptosis in a Dynamic Bioprinted Placenta Model. Biotechnology and Bioengineering, 116(1): 181-192, 2019 Jan. PMID: 30298908, PMCID: PMC6289739, DOI: 10.1002/bit.26850

Navarro J, Swayambunathan J, Lerman M, Santoro M, Fisher JP. Development of Keratin-Based Membranes for Potential Use in Skin Repair. Acta Biomaterialia, 83: 177-188, 2019 Jan. PMID: 30342286, PMCID: PMC6380884, DOI: 10.1016/j.actbio.2018.10.025

Smith BT, Bittner SM, Watson E, Smoak MM, Diaz-Gomez L, Molina ER, Kim YS, Hudgins CD, Melchiorri AJ, Scott DW, Grande-Allen JK, Yoo JJ, Atala A, Fisher JP, Mikos AG. Multi-Material Dual Gradient 3D Printing for Osteogenic Differentiation and Spatial Segregation. Tissue Engineering Part A, in press.  

Bittner SM, Guo JL, Mikos AG. Spatiotemporal Control of Growth Factors in Three-Dimensional Printed Scaffolds. Bioprinting, 12:e00032, 2018 Dec. PMID: 31106279, PMCID: PMC6519969, DOI: 10.1016/j.bprint.2018.e00032

Whitely M, Cereceres S, Dhavalikar P, Salhadar K, Wilems T, Smith B, Mikos A, Cosgriff-Hernandez E. Improved In Situ Seeding of 3D Printed Scaffolds Using Cell-Releasing Hydrogels. Biomaterials, 185: 194-204, 2018 Dec. PMID: 30245387, PMCID: PMC6298753, NIHMSID:1508287, DOI: 10.1016/j.biomaterials.2018.09.027

Guo T, Noshin M, Baker HB, Taskoy E, Meredith SJ, Tang Q, Ringel JP, Lerman MJ, Chen Y, Packer JD, Fisher JP. 3D Printed Biofunctionalized Scaffolds for Microfracture Repair of Cartilage Defects. Biomaterials, 185: 219-231, 2018 Dec. PMID: 30248646, PMCID: PMC6186501, DOI: 10.1016/j.biomaterials.2018.09.022

Bittner SM, Guo JL, Melchiorri AJ, Mikos AG. Three-Dimensional Printing of Multilayered Tissue Engineering Scaffolds. Materials Today, 21(8): 861-874, 2018 Oct. PMID: 30450010, PMCID: PMC6233733, DOI: 10.1016/j.mattod.2018.02.006

Kim YS, Majid M, Melchiorri AJ, Mikos AG. Applications of Decellularized Extracellular Matrix in Bone and Cartilage Tissue Engineering. Bioengineering & Translational Medicine, 4(1): 83-95, 2018 Oct. PMID: 30680321, PMCID: PMC6336671, DOI: 10.1002/btm2.10110

Lerman MJ, Lembong J, Muramoto S, Gillen G, Fisher JP. The Evolution of Polystyrene as a Cell Culture Material. Tissue Engineering Part B: Reviews, 24(5): 359-372, 2018 Oct. PMID: 29631491, PMCID: PMC6199621, DOI: 10.1089/ten.teb.2018.0056

Patel DB, Santoro M, Born LJ, Fisher JP, Jay SM. Towards Rationally Designed Biomanufacturing of Therapeutic Extracellular Vesicles: Impact of the Bioproduction Microenvironment. Biotechnology Advances, 36(8): 2051-2059, 2018 Sept. PMID: 30218694, PMCID: PMC6250573, DOI: 10.1016/j.biotechadv.2018.09.001

Smith BTS, Lu A, Watson E, Santoro M, Melchiorri AJ, Grosfeld EC, van den Beucken JJJP, Jansen JA, Scott DW, Fisher JP, Mikos AG. Incorporation of Fast Dissolving Glucose Porogens and Poly(lactic-co-glycolic acid) Microparticles within Calcium Phosphate Cements for Bone Tissue Regeneration. Acta Biomaterialia, 78: 341-350, 2018 Sep. PMID: 30075321, PMCID: PMC6650161, NIHMSID:989101, DOI: 10.1016/j.actbio.2018.07.054

Guo T, Ringel JP, Lim CG, Bracaglia LG, Noshin M, Baker HB, Powell DA, Fisher JP. Three Dimensional Extrusion Printing Induces Polymer Molecule Alignment and Cell Organization within Engineered Cartilage. Journal of Biomedical Materials Research, Part A, 106(8): 2190-2199, 2018 Aug. PMID: 29659132, PMCID: PMC6030456, DOI: 10.1002/jbm.a.36426

Gao T, Gillispie GJ, Copus JS, Asari AKPR, Seol Y-J, Atala A, Yoo JJ, Lee SJ. Optimization of Gelatin-Alginate Composite Bioink Printability Using Rheological Parameters: A Systematic Approach. Biofabrication, 10(3):034106, 2018 Jun. PMID: 29923501, PMCID: PMC6040670, DOI: 10.1088/1758-5090/aacdc7

Seol Y-J, Lee H, Copus JS, Kang H-W, Cho D-W, Atala A, Lee SJ, Yoo JJ. 3D Bioprinted Biomask for Facial Skin Reconstruction. Bioprinting, 10:e00028, 2018 Jun. PMID: 30911695, PMCID: PMC6430133, DOI: 10.1016/j.bprint.2018.e00028

Moroni L, Burdick JA, Highley C, Lee SJ, Morimoto Y, Takeuchi S, Yoo JJ. Biofabrication of 3D Tissue Models and Regenerative Medicine. Nature Reviews Material, 3(5): 21-37, 2018 May. PMID: 31223488; PMCID: PMC6586020, DOI: 10.1038/s41578-018-0006-y

Kim SH, Yeon YK, Lee JM, Chao JR, Lee YJ, Seo YB, Sultan MT, Lee OJ, Lee JS, Yoon IS, Hong IS, Khang G, Lee SJ, Yoo JJ, Park CH. Precisely Printable and Biocompatible Silk Fibroin Bioink for Digital Light Processing 3D Printing. Nature Communications, 9(1): 1620, 2018 Apr. PMID: 29693652, PMCID: PMC5915392, DOI: 10.1038/s41467-018-03759-y

Wang Z, Lee SJ, Cheng HJ, Yoo JJ, Atala A. 3D Bioprinted Functional and Contractile Cardiac Tissue Constructs. Acta Biomaterialia, 70: 48-56, 2018 Apr. PMID: 29452273, PMCID: PMC6022829, NIHMSID: NIHMS973066, DOI: 10.1016/j.actbio.2018.02.007

Santoro M, Navarro J, Fisher JP. Micro and Macro Bioprinting: Current Trends in Tissue Modeling and Organ Fabrication. Small Methods, 2(3): 1700318, 2018 Mar. PMID: 30397639, PMCID: PMC6214196, DOI: 10.1002/smtd.2017003318

Miao S, Castro N, Nowicki M, Xia L, Cui H, Zhou X, Zhu W, Lee S, Sarkar K, Vozzi G, Tabata Y, Fisher JP, Zhang LG. 4D Printing of Polymeric Materials for Tissue and Organ Regeneration. Materials Today, 20(10): 577-591, 2017 Dec. PMID: 29403328, PMCID: PMC5796676, DOI: 10.1016/j.mattod.2017.06.005

Tang Q, Piard C, Lin J, Nan K, Guo T, Caccamese J, Fisher JP, Chen Y. Imaging Stem Cell Distribution, Growth, Migration, and Differentiation in 3-D Scaffolds for Bone Tissue Engineering Using Mesoscopic Fluorescence Tomography. Biotechnology and Bioengineering, 115: 257-265, 2017 Sept. PMID: 28921540, PMCID: PMC5699959, DOI: 10.1002/bit.26452

Skardal A, Murphy SV, Devarasetty M, Mead I, Kang HW, Seol YJ, Shrike ZY, Shin SR, Zhao L, Aleman J, Hall AR, Shupe TD, Kleensang A, Dokmeci MR, Lee SJ, Jackson JD, Yoo JJ, Hartung T, Khademhosseini A, Soker S, Bishop CE, Atala A. Multi-Tissue Interactions in an Integrated Three-Tissue Organ-on-a-Chip Platform. Scientific Reports, 7(1): 8837, 2017 Aug. PMID: 28821762, PMCID: PMC5562747, DOI: 10.1038/s41598-017-08879-x

Bracaglia LG, Smith BT, Watson E, Arumugasaamy N, Mikos AG, Fisher JP. 3D Printing for the Design and Fabrication of Polymer-Based-Gradient Scaffolds. Acta Biomaterialia, 56: 3-13, 2017 Jul. PMID: 28342878, PMCID: PMC5544968, DOI: 10.1016/j.actbio.2017.03.030

Kuo CY, Baker HB, Fries MH, Yoo JJ, Kim PCW, Fisher JP. Bioengineering Strategies to Treat Female Infertility. Tissue Engineering Part B: Reviews, 23(3): 294-306, 2017 Jun. PMID: 28034338, PMCID: PMC5911692, DOI: 10.1089/ten.TEB.2016.0385

Guo T, Holzberg TR, Lim CG, Gao F, Gargava A, Trachtenberg JE, Mikos AG, Fisher JP. 3D Printing PLGA: A Quantitative Examination of the Effects of Polymer Composition and Printing Parameters on Print Resolution. Biofabrication, 9(2): 024101, 2017 Apr. PMID: 28244880, PMCID: PMC5808938, DOI: 10.1088/1758-5090/aa6370

Trachtenberg JE, Placone JK, Smith BT, Fisher JP, Mikos AG. Extrusion-Based 3D Printing of Poly(Propylene Fumarate) Scaffolds with Hydroxyapatite Gradients. Journal of Biomaterials Science: Polymer Edition, 28(6): 532-554, 2017 Apr. PMID: 28125380, PMCID: PMC5597446, DOI: 10.1080/09205063.2017.1286184

Zhang K, Fu Q, Yoo J, Chen X, Chandra P, Mo X, Song L, Atala A, Zhao W. 3D Bioprinting of Urethra with PCL/PLCL Blend and Dual Autologous Cells in Fibrin Hydrogel: An in vitro Evaluation of Biomimetic Mechanical Property and Cell Growth Environment. Acta Biomaterialia, 50: 154-164, 2017 Mar. PMID: 27940192, DOI: 10.1016/j.actbio.2016.12.008